Emerging infectious diseases (EIDs) are a challenge for public health wall-e bearbrick and biosurveillance infrastructure across the globe.These etiological agents, which cause EIDs, are primarily of zoonotic origin.Due to the complexity of zoonotic pathogens, research and response to EIDs must be a transdisciplinary effort.While crisis and circums
Lin Feng,1,2 Xiaozhe Yang,1,2 Yanfeng Shi,1,2 Shuang Liang,1,2 Tong Zhao,1,2 Junchao Duan,1,2 Zhiwei Sun1,2 1Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, PR China; 2Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, PR China Backgro
Acute lymphoblastic leukemia (ALL) with lutron rrst-8ans-wh recurrent genetic lesions, affecting a series of kinase genes, is associated with unfavorable prognosis, however, it could benefit from treatment with tyrosine kinase inhibitors (TKI).NUP214::ABL1 fusion is detected in 6% of T-cell acute lymphoblastic leukemia (T-ALL), and is very rare in
Abstract The molecular identity and pharmacological properties of mechanically gated ion channels in sensory neurons are poorly understood.We show that FM1-43, a styryl dye used to fluorescently label cell membranes, permeates mechanosensitive ion channels in cultured dorsal root ganglion neurons, resulting in blockade of three previously defined s
In the Early Cretaceous Jehol Biota, the toothless pterosaurs flourished with the chaoyangopterids and tapejarids playing a key role in understanding the early diversity and evolution of the Azhdarchoidea.Unlike the more diverse tapejarids, the rarer chaoyangopterids are characterized by a long and low rostrum, supporting a close relationship with